Start by developing a workout routine, and create a plan for your diet. In my personal opinion, I wouldn't obsess about getting laid until your mind is in a better place. Have you considered therapy? I understand how debilitating depression can be, and want to point out that it is often a call to action. It will be tough in the beginning, but developing healthy habits will help tons.

Do you care how you lose your virginity? Do you want it to be with some you deem special or could it be with anyone you find attractive?